Study looks at Plavix's role in ulcer risk

01/20/2005 | NYTimes.com

The study in today's New England Journal of Medicine found the anti-stroke drug's risk of ulcers was 12 times greater for patients than those who took aspirin in combination with a heartburn pill. Nearly half of Plavix users take the drug because doctors assume it is safer on the stomach than aspirin, but the study says the guidelines should be changed and those taking Plavix should consider changing to the aspirin-heartburn drug tandem instead. A spokesman for Bristol-Myers Squibb, which co-markets the drug with Sanofi-Aventis, questioned the study, saying the differences in ulcers could be because of the heartburn pill.

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