High sclerostin levels seen in some diabetes patients

01/28/2013 | PhysiciansBriefing.com

Type 2 diabetes patients with atherosclerotic disease showed higher circulating levels of sclerostin, a study in Diabetes Care found. Carotid plaques in males and abnormal intima-media thickness and aortic calcification in both males and females were linked to increased levels of sclerostin, researchers said. A sclerostin cutoff of 42.3 pmol/L showed a 69% sensitivity and a 54.8% specificity in predicting atherosclerotic disease risk, researchers found.

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