Discovery raises hope for xenotransplantation of pig lungs

Pig lungs kept alive and functioning with human blood were working well five to six hours after an experiment using a device that mimics the human circulation system and a procedure that replicates traditional lung transplants, an Australian researcher said. As part of the experiment, researchers first removed a portion of pig DNA that makes the animal's organs incompatible with human blood and added human DNA to control blood-clotting and prevent rejection in humans. The researchers say their hope is that clinical trials of animal-to-human transplants of pig lungs could be conducted in five to 10 years.

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