Investigational drug shows promise for GERD patients

02/3/2010 | Medscape (free registration)

Long-acting arbaclofen placarbil reduced acid reflux episodes in gastroesophageal reflux disease patients over a 12-hour period, according to a report in the American Journal of Gastroenterology. The treatment is an investigational prodrug of the active R-isomer of baclofen, which has been used for GERD but is limited by a short half-life and poor tolerability.

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