Scientists tweak protein receptors to make mice numb to cold

02/15/2013 | Medical News Today

Brain researchers at the University of Southern California have developed a technique to block the sensation of cold in laboratory mice, while still enabling them to feel touch and heat. In an experiment, the neuroscientists were able to manipulate a protein referred to as TRPM8 -- which is also present in humans -- that acts as a sensor of cold temperatures in neurons in the skin. The researchers say their findings could lead to a new class of pain medications that don't leave patients completely numb.

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