Radioisotope tracks spreading SIV in macaques

02/15/2014 | Nature (free content)

Scientists detected simian immunodeficiency virus in live rhesus macaques using SIV antibodies tagged with copper-64 for detection with PET/CT imaging. Images showed that the virus replicated extensively in the large intestines, lymph nodes, spleen and nose. Residual signals were detected in the small intestines, lymphatic system and male reproductive tract even in cases where the virus was undetectable. The data suggest the method might play a role in management of HIV, a similar disease, researchers said.

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