Despite advances in medicine and strict regulation, patients often are reluctant to enter U.S. clinical trials, clinicians say, posing a barrier to medical advances. "Patients get very concerned that they’re made as a 'guinea pig' when they hear the word 'trial,'" said oncologist Dr. Trina Poretta. "But that's not at all the case, because this is how we've advanced medicine." In addition, Dr. Ronald Librizzi cited the difficulty of disseminating knowledge of cutting-edge treatments to practicing physicians.
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