Research challenges periprocedural MI biomarker threshold

03/6/2012 | TheHeart.org (Montreal) (free registration)

Researchers from the Harvard Clinical Research Institute say the current troponin cutoff to determine periprocedural MI is too sensitive and should be adjusted. "The major finding from our paper is when CK-MB and troponin are both used to diagnose periprocedural MI, they diagnose very different events if they are taken at the same threshold of three times the [upper limit of normal] ULN, which is the current task force definition," senior author Dr. Donald E. Cutlip said.

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