Researchers are using deep brain stimulation to treat patients with severe and treatment-resistant anorexia nervosa. The study, published in the Lancet, was initiated to test the safety of DBS, but it was also able to show the treatment can lead to improvements in body mass index and mood. The study used MRI to visualize the subcallosal cingulate, the target for the procedure, and patients also underwent PET imaging before and after DBS. Assessment of PET images indicated "changes in cerebral glucose metabolism that were consistent with a reversal of the abnormalities seen in the anterior cingulate insula and parietal lobe in the disorder," researchers said.
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