Study shows Genentech drug may damage growing bones

03/10/2008 | Yahoo!

U.S. researchers found that HhAntag -- a cancer drug that has shown potential in eliminating medulloblastoma tumors -- caused permanent bone defects in young mice. The Genentech drug is a signal transduction inhibitor that blocks the Hedgehog gene's cancer-inducing effects. Though the study results suggest the drug is risky for use in children, it "may still represent a highly promising approach to treating pediatric cancer," the lead researcher said.

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