A study in the journal Nature has found that hematopoietic stem cells need a highly regulated protein synthesis rate to function properly, and any increase or decrease can impair stem cell functioning. Using a reagent to measure cells' levels of protein synthesis, the study team found that protein production was lower in HSCs in vivo than in most hematopoietic cells. Protein synthesis could serve as an indicator of cellular function and health for various kinds of cells, researchers suggested.
Regulation of protein synthesis is crucial for hematopoietic stem cells
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