Swiss, U.K. researchers block faulty genes to slow ALS in mice

03/14/2005 | Times (London) (subscription required), The

In two separate trials, tests suggested that using gene therapy to interfere with a faulty SOD1 gene slowed the progression of a disease in mice similar to amyotrophic lateral sclerosis in humans. The teams used lentiviruses to deliver a healthy version of the gene to the mice to delay onset of the disease and prolong their lives, offering hope for a treatment for human sufferers of the degenerative disease, according to studies in Nature Medicine.

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