Blocking prostaglandin with nonsteroidal anti-inflammatory drugs helps stem cells leave the bone marrow and enter the bloodstream, where they can be collected for use in therapies, according to a study in the journal Nature. The drugs can be linked to fewer adverse effects compared with other methods, according to researchers, who looked at humans, mice and baboons. Charles Craddock, director of the blood and marrow transplant unit at Queen Elizabeth Hospital in Birmingham, England, said the findings could lead to better methods for integrating the cells with bone marrow in transplant recipients.
NSAIDS may boost the number of cells collected for transplants
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