Scientists redesign yeast chromosome to control genetic mutations

04/1/2014 | Los Angeles Times (tiered subscription model)

Jef Boeke, director of the NYU Langone Medical Center's Institute for Systems Genetics, and a team of scientists have modified one chromosome of the Saccharomyces cerevisiae, a yeast used for brewing beer as well as making bread and biofuels. The "synthesized" chromosome lacks certain genes that cause mutations, allowing the scientists to control the mutation of the yeast. "We have a yeast that looks, smells and behaves like a regular yeast, but this yeast is endowed with properties normal yeast don't have," Boeke said.

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