Gene variants tied to diabetes don't affect GLP-1 in healthy people

04/4/2012 | PhysiciansBriefing.com

A study in Diabetes found variants in the genes TCF7L2, WFS1 and KCNQ1, which are linked to type 2 diabetes, did not trigger GLP-1-induced insulin secretion in healthy individuals. The presence of the genetic variants also did not appear to impact beta-cell responsiveness to GLP-1 infusion and hyperglycemia, researchers noted.

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