2 approved drugs show promise in treating prion disease

04/4/2013 | Yahoo

Researchers have found that two drugs already approved for use in humans -- tacrolimus and astemizole -- reduce the amount of prion protein present on cell surfaces by about 70%. Misfolded forms of the proteins are believed to cause such diseases as Creutzfeldt-Jakob disease. Astemizole is the most promising because it is effective at relatively low doses, while tacrolimus can cause neurotoxicity.

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