Scientist target glucagon pathway for treating type 2 diabetes

04/12/2012 | HealthDay News

Inhibiting the CaMKII enzyme glucagon pathway helped lower blood glucose and cholesterol levels, prevent fatty liver deposits and boost insulin sensitivity without adverse effects in obese mice with type 2 diabetes, a study in Cell Metabolism showed. "When you eat a meal and your sugar goes up, glucagon and glucose should switch off, but that doesn't happen in type 2 diabetes," said Dr. Vivian Fonseca, president for medicine and science at the American Diabetes Association.

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