Researchers: New method needed in dengue vaccine development

04/16/2013 | Yahoo

Researchers from the La Jolla Institute for Allergy and Immunology have found that, contrary to common belief, T cells actually are part of a mechanism to control dengue virus infection. "The current thinking in the field is that the goal of a dengue vaccine should be the induction of antibodies and not T cells. But our results suggest that both cell types are needed to produce a strong immune response against dengue infection," said scientist Alessandro Sette. The finding, published in the journal Proceedings of the National Academy of Sciences, suggests that a new approach to dengue vaccine development may be needed.

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