Publication bias overstates effectiveness of SRIs for autism

04/23/2012 | Huffington Post, The

A review of 10 randomized, double-blind, controlled trials on the effectiveness of serotonin reuptake inhibitors for treating repetitive behaviors in autism showed a publication bias overstating the drug's benefits. Published trials found that the drug yielded small improvements in patients with autism, but after taking into account unpublished trials, the improvement lost its significance, researchers reported in the journal Pediatrics.

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