Review ties high doses of some NSAIDs to heart risks

05/29/2013 | MedPage Today (free registration)

A meta-analysis in The Lancet found high doses of some frequently used nonsteroidal anti-inflammatory drugs were associated with an elevated risk of major vascular events, primarily heart attack. However, researchers said the findings "indicate that the effects of different regimens in particular patients can be predicted, which may help physicians choosing between alternative NSAID regimens to weigh up which type of NSAID is safest in different patients."

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