Leukemia study finds mutation that limits blood stem cells

06/5/2013 | Genetic Engineering & Biotechnology News

Researchers have discovered that a single mutation in the leukemia-associated gene JAK2 can reduce the ability of blood stem cells to replicate. The mutation is commonly present in patients with myeloproliferative neoplasms. The team plans to further study the effect of additional mutations on cells, which could provide clues on how leukemia develops. The findings were reported in PLOS Biology.

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