4 genes turn cells into blood vessel precursors

06/14/2013 | Yahoo

Researchers at the Icahn School of Medicine at Mount Sinai in New York transferred four genes -- Gata2, Gfi1b, cFos and Etv6 -- into mouse fibroblast cells and were able to create cells that function like hematopoietic stem cells. "The cells that we grew in a petri dish are identical in gene expression to those found in the mouse embryo and could eventually generate colonies of mature blood cells," lead author Carlos Filipe Pereira said. The study was reported in the journal Cell Stem Cell.

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