Location of cancer matters in treatment

06/15/2010 | New York Times (tiered subscription model), The

Proponents of targeted cancer drugs have long said that a tumor's genetic composition, rather than its location, would someday drive treatment. But recent trials of drugs that target specific tumor mutations have failed to affect tumors with the same mutations in a different location. "We've gone through a very rapid period of high expectations, maturation and disappointments," said Dr. J. Leonard Lichtenfeld of the American Cancer Society.

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