Researchers at National Jewish Health and the University of Colorado Anschutz Medical Campus have identified the peptide that causes diabetes in mice. "Our findings contradict conventional wisdom, which suggests that insulin peptides that are well-presented to the immune system trigger diabetes. ... The peptide we identified triggers diabetes precisely because it is so poorly presented to the immune system," said John Kappler, a professor of immunology at National Jewish Health. The discovery could lead to developments in the study of diabetes in humans.
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