Amyloid-beta deposits can lead to more cerebral microhemorrhages

06/19/2011 | Medscape (free registration)

Australian researchers using PET with Pittsburgh Compound B found that people with amyloid-beta deposits in the brain show higher rates of cerebral microhemorrhages, even when they do not inhibit normal symptoms. "If you're PiB-positive and are healthy, your risk of having a microhemorrhage is just as high as, if not higher than, those with mild cognitive impairment or Alzheimer's disease," said lead author Dr. Christopher Rowe, professor of nuclear medicine at Austin Hospital in Victoria, Australia. The study presented at the SNM annual meeting in San Antonio indicates that the presence of microhemorrhages can provide clues on accumulation of amyloid beta and the cognitive decline that could follow.

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