Research uncovers molecule's role in inhibiting organ rejection

06/23/2008 | Forbes

Scientists found that an immune molecule known as HLA-G dimer can help prevent organ- and tissue-transplant rejection in patients by binding to its inhibitory receptor ILT4 to activate a signaling pathway in which immune molecules IL-6 and STAT3 play a role. They believe that boosting the molecule's mechanism can curb immune activity in patients with autoimmune disorders and organ transplants.

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