Antifungal nanoparticles may help burn victims

07/2/2013 |

Nanoparticle-encapsulated amphotericin b significantly reduced fungal biofilm activity in a burn wound model, compared with an untreated control model, researchers found. AmB-np also resulted in more advanced re-epithelialization, organized dermal proliferation and appropriate dermal remodeling compared with solubilized AmB and an untreated control model, according to the study in Nanomedicine: Nanotechnology, Biology, and Medicine. AmB can be toxic to the liver at high doses and encapsulating it might reduce toxicity and allow topical burn treatment, the researchers said.

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