Study of HIV-immune patients yields path to antibody precursors

07/19/2013 | InfectionControlToday.com

A Scripps Research Institute-led team studied antibodies from the blood of people whose immune systems can find and neutralize HIV. Scientists reverse-engineered molecules that triggered precursors to HIV-fighting antibodies and are hopeful that the technique could be useful in developing a vaccine. "What we tried to do was to learn how those antibodies developed over the course of natural infection and attempt to guide the immune response in the direction of what we know works in certain HIV-infected individuals," biologist Jean-Philippe Julien said.

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