Cocaine addicts respond better to topiramate plus CBT

07/26/2013 | Medscape (free registration)

Patients undergoing withdrawal symptoms due to cocaine and alcohol addiction who received the seizure drug topiramate in combination with cognitive behavioral therapy for 13 weeks had a higher likelihood of abstaining from cocaine than those who received placebo and CBT, a 170-patient study found. However, the groups did not differ in terms of total reduction in cocaine or alcohol consumption or in cocaine cravings, researchers reported in the journal Drug and Alcohol Dependence.

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