Pilocytic astrocytomas in children may contain fewer mutations

07/28/2013 | Oncology Nurse Advisor online

A whole-genome sequencing of 96 pilocytic astrocytomas, the most common pediatric brain tumor, revealed that mitogen-activated protein kinase mutations were the only frequent mutations that could promote cancer development in the tumors. German researchers reported in the journal Nature Genetics that the genomes of these tumors had far fewer mutations compared with those found in medulloblastomas.

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