A new study does not support previous evidence of a connection between glucose metabolism abnormalities and Alzheimer's disease, according to data published in JAMA Neurology. Researchers categorized participants enrolled in the Baltimore Longitudinal Study of Aging into two groups. The first cohort consisted of 197 participants who had at least two oral glucose tolerance tests during life and a brain autopsy after death, and the second consisted of 53 living participants who also underwent two or more OGTTs and PET scans using beta-amyloid tracer C-11 Pittsburgh Compound B. Findings showed no relationship between OGTT results and brain pathology.
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