In the first known such case, an immunocompromised patient died after exposure to West Nile virus through blood products. A minipool of six blood donations was implicated. Blood products have been screened for West Nile since 2003. In this case, the individual samples tested negative but the pool was reactive for the virus, a situation deemed acceptable for transfusion by the FDA. Moving forward, minipools in which the reactive donation can't be identified and removed will be discarded.
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