Computer program holds promise for drug repositioning

08/18/2011 | Wall Street Journal, The

Scientists at Stanford University developed a computer program that looks at NIH public databases containing genomic studies to identify drugs already on the market that could be repurposed to treat other diseases. Through the program, the researchers found that an epilepsy drug, topiramate, might reduce symptoms of inflammatory bowel disease, while cimetidine, an ulcer drug, might delay progression of lung tumors. The findings, published in Science Translational Medicine, need to be validated through further study, said Rochelle Long of the National Institute of General Medical Sciences.

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