H1N2 vaccine increases piglets' susceptibility to H1N1

09/2/2013 | MedicalXpress.com

Piglets vaccinated for H1N2 influenza developed worse lung infections when challenged with H1N1 compared with those not vaccinated against H1N2. Vaccine-associated enhanced respiratory disease occurs when a vaccine induces antibodies against one virus that facilitate the infection process of another, related virus. The findings may help direct development of a universal influenza vaccine for humans.

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