STEMI patients who received metoprolol before undergoing primary PCI experienced smaller infarcts and higher left ventricular ejection fractions, according to data published in Circulation. "Infarct size is a major determinant of post-infarction mortality," the researchers wrote. "... Here, we show that an inexpensive medication already approved for STEMI treatment ... can significantly reduce infarct size simply by being administered before reperfusion."
Published in Brief: