New imaging agents could show tumors earlier

10/9/2011 | ScienceDaily

Recent research identified new PET scan imaging compounds that detect inflammation and tumors. The agents are derived from cyclooxygenase-2 (COX-2) enzyme inhibitors, and since COX-2 is not in most normal tissues and is present in tumors and inflammatory lesions, it is a useful tool for imaging. "As a tumor grows and becomes increasingly malignant, COX-2 levels go up," said Lawrence Marnett, Ph.D., director of the Vanderbilt Institute of Chemical Biology.

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