Experts ID new technique to diagnose cancer mutations

10/16/2011 | PhysiciansBriefing.com

The use of mutant enrichment with 3-foot-modified oligonucleotides showed significant concentration- and thermodynamics-dependent sensitivities in detecting cancer mutations in medical specimens, a study found. Experts also found that MEMO was able to block normal allele extension and enable mutated allele extension. The findings suggest that MEMO is a simple and highly sensitive technique for detecting cancer mutations, Korean researchers reported in The Journal of Molecular Diagnostics.

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