Scientists find potential target for Parkinson's disease

10/18/2012 | Scientist, The

Researchers found the same deformities in the nuclear membrane of neural stem cells in brain tissue samples from deceased Parkinson's disease patients and found that correcting the mutation that causes the deformities reverses the phenotype. Researchers with the Salk Institute for Biological Studies studied induced pluripotent stem cells derived from Parkinson’s patients carrying the luceine-rich repeat kinase 2 mutation previously associated with the disease, then repaired the cells in vitro. The research, published in the journal Nature, "is a way for us to start asking questions about how we can use a selective small molecule to maybe reverse a disease phenotype for Parkinson's," said Jeremy Nichols, a researcher at The Parkinson’s Institute.

View Full Article in:

Scientist, The

Published in Briefs:

SmartBrief Job Listings for Health Care

Job Title Company Location
U.S. DEPARTMENT OF HEALTH & HUMAN SERVICES Food and Drug Administration Office of the Chief Counsel
Silver Spring, MD, MD
Counsel – Regulatory Affairs
RAI Services Company
Winston Salem, NC
Senior Manager, Clinical Affairs - Advanced Technology
Edwards Lifesciences
Irvine, CA
Director, Litigation & Investigations EMEA
Gilead Sciences
Stockely Park
Assistant General Counsel/Senior Corporate Counsel
South San Francisco, CA