Neutrophils may help patients who receive tissue transplants

10/29/2013 | MedicalXpress.com

Neutrophils, a type of white blood cell, play an important role in preventing tissue injury, and new findings about a key protein complex could lead to treatments that help tissue-transplant patients, according to a study in the journal Developmental Cell. The protein complex made up of CCM3 and STK24 governs neutrophils' release of granules. "This study, by revealing the basic cellular function of CCM3, also points a new direction for the investigation of the pathogenic basis for cerebral cavernous malformation (CCM) disease," said senior author Dianqing Wu of Yale University.

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