Researchers study cyclodextrin as alternative to Lorenzo's Oil

11/8/2011 | Wall Street Journal, The

The compound cyclodextrin, a treatment for the rare disease Niemann-Pick Type C, is also being tested for conditions including Alzheimer's disease and the HIV virus. But some researchers are hoping it can work against the neurological disease adrenoleukodystrophy, or ALD. Mixing fatty acids extracted from rapeseed and olive oils has been shown to slow progress of the disease. Recently, Boston University scientists reported experiments in rats that showed that cyclodextrin quickly removed the fatty-acid buildup that characterizes ALD.

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