Dapagliflozin shows efficacy as add-on to sitagliptin

11/14/2013 | Medscape (free registration)

Type 2 diabetes patients who used dapagliflozin as an add-on to sitagliptin treatment attained a 24.9% increase in beta-cell function from baseline, compared with a 5.2% increase in the placebo group, according to a study in Diabetes Care. Researchers also found more patients in the dapagliflozin arm had A1C levels below 7.0% than those who took a placebo. However, dapagliflozin was tied to higher genital infection rates in patients, researchers added.

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