Research links genetic defects to ulcerative colitis

11/16/2009 | BBC

A British study that included 12,700 people found defects in four genes that help keep the lining of the intestines healthy may be a cause of ulcerative colitis. The genes affect the seals between cells of the epithelium, and researchers said genetic defects may cause bacteria to leak into the intestine and trigger an immune reaction leading to chronic inflammation.

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