Bypassing live-mosquito test could quicken malaria-vaccine trials

11/21/2012 | SciDev.net

Injecting a formulation of malaria parasites into healthy subjects, instead of following usual trials that expose humans to infected mosquitoes, could accelerate clinical testing of malaria vaccines, according to a study in the American Journal of Hygiene and Tropical Medicine. The approach helps researchers ensure that volunteers have the same infection dose. "For the first time, this will allow investigators in any clinical facility in the world to test malaria drugs. It is going to change the face of testing of these new products," said study co-author Stephen Hoffman.

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