CFS: 3-MCPD esters unlikely to be toxic

11/27/2012

Fatty acid esters of 3-monochloropropane-1,2-diol in food are unlikely to have major toxic effects on local consumers, according to a study by Hong Kong's Centre for Food Safety. Many questions remain about 3-MCPD, a potentially carcinogenic process contaminant in its esterified form, concerning its toxicology, its metabolic fate in the human gut, and methods of analysis. "The Joint FAO/WHO Expert Committee on Food Additives established a provisional maximum tolerable daily intake (PMTDI) of 2 μg/kg body weight/day for 3-MCPD," a CFS statement noted." Assuming that 100 percent of the toxic 3-MCPD was released from its fatty acid esters by hydrolysis in the digestive system, the dietary exposures to 3-MCPD for average and high adult consumers were only 10% and 26% of the PMTDI, respectively, which were way below the PMTDI." The CFS report, a news release, and a PowerPoint presentation based on the report are available online.

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