Study raises concerns about atypical antipsychotic use

11/29/2012 | Medscape (free registration)

Four atypical antipsychotic drugs often prescribed off-label to older adults may not be safe or effective, according to researchers at the University of California, San Diego. The study in the Journal of Clinical Psychiatry looked at the drugs aripiprazole, olanzapine, quetiapine and risperidone and found a high discontinuation rate and no significant improvements. Study authors said the use of these drugs in older patients is a "major clinical dilemma."

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