Obesity pill Contrave is effective but poses risks, FDA reviewers say

12/5/2010 | Wall Street Journal, The

FDA staff members said Orexigen Therapeutics and Takeda Pharmaceutical's weight-loss pill Contrave has achieved one of the agency's requirements for efficacy, but it causes side effects related to hypertension in some obese patients. An advisory panel is scheduled this week to review the drug, which is a combination of antidepressant bupropion and addiction treatment naltrexone.

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