Blocking gene pathway thwarts insulin resistance in mice

12/7/2012 | HealthDay News

Switching off the JNK genetic pathway helped prevent insulin resistance, but not weight gain, in mice fed a high-fat diet, a study in the journal Science indicated. "What we discovered is the JNK genes in the macrophages are critical for the ability of macrophages to cause inflammation, specifically in response to feeding or eating a high-fat diet," said study author Roger Davis.

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