Researchers find method to improve single-cell genome sequencing

12/30/2012 | Chemical & Engineering News

Researchers have developed an amplification method that enhances the process of single-cell genome sequencing. The process, called multiple annealing and looping-based amplification cycles, "is about halfway home in terms of making single-cell genome sequencing comparable to bulk DNA sequencing in terms of the uniformity," said Jay A. Shendure of the University of Washington, Seattle. "That is perhaps the clearest indicator that we view it as a potentially important advance."

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