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Maternal gestational diabetes exposure ups insulin resistance risk in youths

Researchers looked at 437 adolescents and found that those who were prenatally exposed to maternal gestational diabetes had insulin resistance, shown by a higher homeostatic model assessment of insulin resistance-2 value and lower Matsuda index, and significantly greater HOMA2-B, compared with those who were not exposed to prenatal GD. The findings, presented at the American Diabetes Association's meeting, revealed that metabolic abnormalities in adolescents were also associated with intrauterine exposure to maternal pre-pregnancy obesity.

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