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Study links type 1 diabetes to certain gene groups

UK researchers evaluated data from the UK Biobank involving 120,000 individuals with the highest genetic risk for type 1 diabetes, from birth to age 60, and found that those with the DR3/DR4 gene group had a 4.2% increased odds of developing the disease, compared with 3.5% among those with DR4/DR4 genes and 1.2% for DR3/DR3 carriers. The findings, presented at the annual meeting of the European Association for the Study of Diabetes, revealed that 71% of type 1 diabetes diagnoses tied to the DR4/DR4 genotype were in those older than 30.

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